Both will speak to the Saban Forum, an annual event organized by the Brookings Institution and entertainment mogul Haim Saban. Saban is also a major political donor who has pledged to support the former secretary of State should she run for president in 2016.
The event will also feature Secretary of State John Kerry and Israeli Prime Minister Benjamin Netanyahu. Netanyahu will appear via sattalite.
Biden and Netanyahu will be the meeting's keynote speakers.
Attendees will discuss the relationship between the U.S. and Israel "via candid closed-door dialogue between U.S. and Israeli officials, policymakers, journalists and business leaders."